3-Isopropyl-5-(4-nitro-2,6-dimethyl-phenoxy)-1H-indole → 4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-dimethylaniline

Beteiligte Stoffe

Reaktionsschritte

11.95 g (36.85 mmol) of nitro compound from Example XIV are hydrogenated in 500 ml of methanol/ethanol mixture using 550 mg of palladium/active carbon (10%) at 3 bar. The mixture is filtered through kieselguhr, the solvent is removed in vacuo and the product is purified by chromatography (toluene/ethyl acetate).

Herkunft & Nachweise