HCID 10223553, compound → HCID 10225497, compound

HRID 1007496Notes

Reaction equation

HRID 1007496 reaction equation
ClC1C=C(C=C(C)[C:8]=1[O:9]C1C=C2C(=CC=1)NC=C2C(C)C)N.[Cl:23][C:24]1[CH:25]=[C:26]([NH:44][C:45](=[O:51])[CH2:46][C:47]([O:49][CH3:50])=[O:48])[CH:27]=[C:28]([CH3:43])[C:29]=1[O:30][C:31]1[CH:32]=[C:33]2[C:37](=[CH:38][CH:39]=1)[NH:36][CH:35]=[C:34]2[CH:40]([CH3:42])[CH3:41]>>[Cl:23][C:24]1[CH:25]=[C:26]([NH:44][C:45](=[O:51])[CH2:46][C:47]([O:49][CH2:50][CH2:8][OH:9])=[O:48])[CH:27]=[C:28]([CH3:43])[C:29]=1[O:30][C:31]1[CH:32]=[C:33]2[C:37](=[CH:38][CH:39]=1)[NH:36][CH:35]=[C:34]2[CH:40]([CH3:41])[CH3:42]

Participants

3

Reactant 2

HCID 10223553HCID 10223553, compoundHCID 22669559HCID 22669559, compound

Product 1

HCID 10225497HCID 10225497, compound

Procedure

This compound can be prepared starting from 3-chloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]-5-methylaniline (Example III) or methyl 3-({3-chloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]-5-methylphenyl}amino)-3-oxo-propanoate (Example 4a) according to methods known from the literature.

Workup

  1. customThis compound can be prepared

Sources & evidence

ORD record
ord-249da1b93dc44dd49236d6d1f4119049
Source dataset
uspto-grants-2004_09
Patent number
US06794406B2

Reaction notes

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