Sodium Hydroxide → HCID 23668093, compound

HRID 1007500Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([NH:22][C:23](=[O:28])[CH2:24][C:25]([OH:27])=[O:26])[CH:5]=[C:6]([CH3:21])[C:7]=1[O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][CH:13]=[C:12]2[CH:18]([CH3:20])[CH3:19].[OH-].[Na+:30]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:22][C:23](=[O:28])[CH2:24][C:25]([O-:27])=[O:26])[CH:5]=[C:6]([CH3:21])[C:7]=1[O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][CH:13]=[C:12]2[CH:18]([CH3:19])[CH3:20].[Na+:30]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 10294443HCID 10294443, compound

Product 1

HCID 23668093HCID 23668093, compound

Procedure

This compound is obtained in a manner analogous to Example 6a starting from 3-({3-chloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]-5-methylphenyl}amino)-3-oxo-propionic acid (Example 6) and sodium hydroxide.

Workup

customThis compound is obtained in a manner analogous to Example 6a

Sources & evidence

ORD record: ord-614d4d30acd24defbd64536993094f1b
Source dataset: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06794406B2

Reaction notes

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