HCID 72650910, compound → HCID 22669657, compound

Participants

Reaction Steps

0.2 g (0.38 mmol) of benzylidene compound from Example 24 are dissolved in 100 ml of methanol and hydrogenated with hydrogen for 18 hours in the presence of palladium on active carbon. The catalyst is filtered off through kieselguhr and the filtrate is concentrated in vacuo. The crude product is purified by chromatography on silica gel 60 in the isocratic gradient mode using toluene/ethyl acetate (10:1).

Provenance & Evidence