HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Cyclohexyl-2-(furan-3-yl)-1H-benzimidazole-5-carboxylic acid → Tyrosine, 3-carboxy-N-[[1-cyclohexyl-2-(3-furanyl)-1H-benzimidazol-5-yl]carbonyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Cyclohexyl-2-(furan-3-yl)-1H-benzimidazole-5-carboxylic acid | HCID 491113 | — |
| Reactant | Racemic 3-(carbomethoxy)tyrosine methyl ester hydrochloride | HCID 69320169 | — |
| Product | Tyrosine, 3-carboxy-N-[[1-cyclohexyl-2-(3-furanyl)-1H-benzimidazol-5-yl]carbonyl]- | HCID 491264 | — |
Reaction Steps
Racemic 3-(carbomethoxy)tyrosine methyl ester hydrochloride (example 119) was coupled to the carboxylic acid of example 2 in the usual manner and saponified to give the tile compound of example 121.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06794404B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-737c640f24ea47dcafe4fb349172556b |
| Source note | uspto-grants-2004_09 |