HuagongsheHuagongshe Chemistry Print Report · For research reference only
trans-2-Phenyl-1-cyclopropanecarbonyl chloride → (1R*,2R*)-N-{2-[2-(4-Amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)ethoxy]ethyl}-2-phenylcyclopropanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | trans-2-Phenyl-1-cyclopropanecarbonyl chloride | HCID 13656 | — |
| Reactant | 1-[2-(2-aminoethoxy)ethyl]-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine | HCID 21913053 | — |
| Product | (1R*,2R*)-N-{2-[2-(4-Amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)ethoxy]ethyl}-2-phenylcyclopropanecarboxamide | HCID 10250832 | — |
Reaction Steps
Using the method of Examples 17-32, trans-2-phenylcyclopropylcarbonyl chloride was reacted with 1-[2-(2-aminoethoxy)ethyl]-2,6,7trimethyl1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The product was purified using Method B. The observed accurate mass was 408.2392.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06797718B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-94ca5ebedd254217a53812e836f0e10d |
| Source note | uspto-grants-2004_09 |