HCID 69595139, compound → HCID 60111235, compound

HRID 1008129Notes

Reaction equation

P(OCCOC(N1C2C(=CC=CC=2)/C(=C/C2NC(C)=CC=2C)/C1=O)=O)(O)(O)=O.CO[O:31][P:32]([O:37][CH2:38][CH2:39][CH2:40][O:41][C:42]([N:44]1[C:52]2[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=2)/[C:46](=[CH:53]/[C:54]2[NH:55][C:56]([CH3:60])=[CH:57][C:58]=2[CH3:59])/[C:45]1=[O:61])=[O:43])([O:34]OC)=[O:33]>>[P:32]([O:37][CH2:38][CH2:39][CH2:40][O:41][C:42]([N:44]1[C:52]2[C:47](=[CH:48][CH:49]=[CH:50][CH:51]=2)/[C:46](=[CH:53]/[C:54]2[NH:55][C:56]([CH3:60])=[CH:57][C:58]=2[CH3:59])/[C:45]1=[O:61])=[O:43])([OH:34])([OH:33])=[O:31]

Participants

Reactant 2

HCID 69595139HCID 69595139, compound

HCID 87904699HCID 87904699, compound

Product 1

HCID 60111235HCID 60111235, compound

Procedure

3-[1-(3,5-Dimethyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-indole-1-carboxylic acid 3-phosphonooxy-propyl ester was prepared using the same procedure for preparing 3-[1-(3,5-dimethyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-indole-1-carboxylic acid 2-phosphonooxyethyl ester but substituting 3-[1-(3,5-dimethyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-indole-1-carboxylic acid 2-(dimethoxy-phosphonooxy)-ethyl ester with 3-[1-(3,5-dimethyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-indole-1-carboxylic acid 3-(dimethoxy-phosphonooxy)propyl ester.

Sources & evidence

ORD record: ord-ad4dd3c22f2549b8909afd21b1a88d1d
Source dataset: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06797725B2

Reaction notes

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