反应详情

A suspension of 3 g 5-chlorosulfonyl-2-oxindole, 1.15 g isopropylamine and 1.2 mL of pyridine in 50 mL of dichloromethane was stirred at room temperature for 4 hours during which time a white solid formed. The solid was collected by vacuum filtration, slurry-washed with hot ethanol, cooled, collected by vacuum filtration and dried under vacuum at 40° C. overnight to give 1.5 g (45%) of 5-isopropylaminosulfonyl-2-oxindole.

1. customformed
2. filtrationThe solid was collected by vacuum filtration
3. washslurry-washed with hot ethanol
4. temperaturecooled
5. filtrationcollected by vacuum filtration
6. customdried under vacuum at 40° C. overnight