6-(3-Methoxyphenyl)-1,3-dihydroindol-2-one → HCID 67281836, compound

HRID 1008170Notes

Reaction equation

HRID 1008170 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]2[CH:17]=[C:16]3[C:12]([CH2:13][C:14](=[O:18])[NH:15]3)=[CH:11][CH:10]=2)[CH:6]=[CH:7][CH:8]=1.[CH3:19][N:20]([CH3:35])[CH2:21][CH2:22][NH:23][C:24]([C:26]1[C:30]([CH3:31])=[C:29]([CH:32]=O)[NH:28][C:27]=1[CH3:34])=[O:25]>>[CH3:19][N:20]([CH3:35])[CH2:21][CH2:22][NH:23][C:24]([C:26]1[C:30]([CH3:31])=[C:29]([CH:32]=[C:13]2[C:12]3[C:16](=[CH:17][C:9]([C:5]4[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=4)=[CH:10][CH:11]=3)[NH:15][C:14]2=[O:18])[NH:28][C:27]=1[CH3:34])=[O:25]

Participants

3

Reactant 2

HCID 105860706-(3-Methoxyphenyl)-1,3-dihydroindol-2-oneHCID 54380946HCID 54380946, compound

Product 1

HCID 67281836HCID 67281836, compoundYield 14%

Procedure

6-(3-Methoxyphenyl)-1,3-dihydroindol-2-one (30 mg, 0.13 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-dimethylaminoethyl)amide (30 mg) to give 8 mg (14%) of the title compound as a yellow-orange solid.

Sources & evidence

ORD record
ord-0c402c0804ec4970a8b00a2192fca1b7
Source dataset
uspto-grants-2004_09
Patent number
US06797725B2

Reaction notes

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