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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1008178Generated: October 30, 2026

N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide → 2,4-Dimethyl-5-(2-oxo-6-pyridin-3-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide

https://huagongshe.com/reaction/1008178

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamideHCID 20761785—
Reactant6-Pyridin-3-yl-1,3-dihydro-indol-2-oneHCID 21915579—
Product2,4-Dimethyl-5-(2-oxo-6-pyridin-3-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amideHCID 6728106333.6%

Reaction Steps

6-Pyridin-3-yl-1,3-dihydroindol-2-one (40 mg, 0.19 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide (50 mg) give 29 mg (33%) of the title compound as a light orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06797725B2
Source datasetuspto-grants-2004_09
ORD IDord-82493a895d4d4a42bcc633048ab5e785
Source noteuspto-grants-2004_09