HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-formyl-2,4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide → 2,4-Dimethyl-5-(2-oxo-6-Pyridin-3-yl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (2-Pyrrolidin-1-Ylethyl) Amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-formyl-2,4-dimethyl-N-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrrole-3-carboxamide | HCID 20761729 | — |
| Reactant | 6-Pyridin-3-yl-1,3-dihydro-indol-2-one | HCID 21915579 | — |
| Product | 2,4-Dimethyl-5-(2-oxo-6-Pyridin-3-yl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (2-Pyrrolidin-1-Ylethyl) Amide | HCID 67281847 | 71% |
Reaction Steps
6-Pyridin-3-yl-1,3-dihydroindol-2-one (60 mg, 0.28 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-pyrrolidin-1-ylethyl)amide (75 mg) to give 90 mg (71%) of the title compound as a light orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06797725B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-155e7636d85c4feba153f0a365e3f3d2 |
| Source note | uspto-grants-2004_09 |