HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Pyridin-3-yl-1,3-dihydro-indol-2-one → 2,4-Dimethyl-5-(2-oxo-6-Pyridin-3-yl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (3-Dimethylaminopropyl) Amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Pyridin-3-yl-1,3-dihydro-indol-2-one | HCID 21915579 | — |
| Reactant | 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-dimethylaminopropyl)amide | HCID 86586209 | — |
| Product | 2,4-Dimethyl-5-(2-oxo-6-Pyridin-3-yl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (3-Dimethylaminopropyl) Amide | HCID 67282839 | 75.9% |
Reaction Steps
6-Pyridin-3-yl-1,3-dihydroindol-2-one (42 mg, 0.2 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-dimethylaminopropyl)amide (50 mg) to give 67 mg (75%) of the title compound as yellow-brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06797725B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-29bc108a99b44520a47be3a6087d9cad |
| Source note | uspto-grants-2004_09 |