HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Phenyloxindole → 2,4-Dimethyl-5-(2-oxo-5-Phenyl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (3-Dimethylaminopropyl) Amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Phenyloxindole | HCID 13301978 | — |
| Reactant | 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-dimethylaminopropyl)amide | HCID 86586209 | — |
| Product | 2,4-Dimethyl-5-(2-oxo-5-Phenyl-1,2-Dihydroindol-3-Ylidenemethyl)-1H-Pyrrole-3-Carboxylic Acid (3-Dimethylaminopropyl) Amide | HCID 67280877 | 28.2% |
Reaction Steps
5-Phenyl-1,3-dihydroindol-2-one (67 mg, 0.32 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-dimethylaminopropyl)amide (81 mg) to give 40 mg (28%) of the title compound as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06797725B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-cf1e4b1b07b145099b8858fbb500abb0 |
| Source note | uspto-grants-2004_09 |