Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 100846Generated: October 30, 2026

Hydrochloric Acid → (-)-1-(9-hydroxy-4-methyl-9-trifluoromethyl-9H-fluorene-2-carbonyl)-azetidine-3-carboxylic acid dimethylamide

https://huagongshe.com/reaction/100846

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantN,N-Dimethyl-3-azetidinecarboxamideHCID 53308703—
Reactant9-hydroxy-4-methyl-9-trifluoromethyl-9H-fluorene-2-carboxylic acidHCID 59492527—
Product(-)-1-(9-hydroxy-4-methyl-9-trifluoromethyl-9H-fluorene-2-carbonyl)-azetidine-3-carboxylic acid dimethylamideHCID 59493074—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-3541818cd78f4310808af022157911f7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)