Methanol → HCID 69780590, compound

Participants

Reaction Conditions

Reaction Steps

1.1 mL of thionyl chloride was added to a cooled solution (ice bath) of 65 mg of amino acid 1i in 4 mL of methanol. After stirring at 50° C. for 3 hours the mixture was concentrated under reduced pressure to give 66 mg of methyl ester 1j. The crude product was used without further purification. 1H-NMR 200 MHz (CD3OD) δ: 3.36-3.59 (2H, m), 3.81 (3H, s), 4.53 (1H, t, J=7 Hz), 7.23 (1H, d, J=7 Hz), 7.60 (1H, d, J=7 Hz), 7.73 (1H, dd, J=9 Hz and J=2 Hz) 7.87 (1H, d, J=2 Hz), 8.47 (1H, d, J=9 Hz),

Provenance & Evidence