HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Methoxyethoxy)benzene-1-sulfonyl chloride → N-[1-(4-Amino-thieno[3,2-c]pyridin-2-ylmethyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-4-(2-methoxy-ethoxy)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Methoxyethoxy)benzene-1-sulfonyl chloride | HCID 22507216 | — |
| Reactant | N-[1-(4-Amino-thieno[3,2-c]pyridin-2-ylmethyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-4-(tetrahydropyran-4-yloxy)-benzenesulfonamide | HCID 22665795 | — |
| Product | N-[1-(4-Amino-thieno[3,2-c]pyridin-2-ylmethyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-4-(2-methoxy-ethoxy)-benzenesulfonamide | HCID 22665719 | — |
Reaction Steps
This compound was prepared from 0.6 mmol 4-(2-methoxy-ethoxy)-benzenesulfonyl chloride and 210 mg (0.5 mmol) of 30a using the procedure described for 58c . Yield: 30 mg (white crystals), m.p. 210° C. (decomp.), EI-MS: 532 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06797710B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-0111ae10246d48dfa01bba5b9d802a8c |
| Source note | uspto-grants-2004_09 |