HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine → 2,3,4,5-Tetrahydro-1,4-benzoxazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine | HCID 22665902 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2,3,4,5-Tetrahydro-1,4-benzoxazepine | HCID 21882775 | 95.9% |
Reaction Steps
10.2 g of 4-benzyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepine were dissolved in 100 mL of ethanol and hydrogenated for 5 hours at room temperature using 1.2 g of palladium (10% on carbon) as catalyst. Filtration followed by removal of the solvent in vacuo gave 6.1 g of 2,3,4,5-tetrahydro-benzo[f][1,4]oxazepine as an oil. EI-MS: 149 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06797710B2 |
| Source dataset | uspto-grants-2004_09 |
| ORD ID | ord-815c93cf37a04f1885adf2c5159f7073 |
| Source note | uspto-grants-2004_09 |