HRID1008539

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID22665621

未命名化合物

结构：CC1CCN(C(=O)C(Cc2cc3c(N)nccc3s2)NS(=O)(=O)c2ccc(OC3CCOCC3)cc2)CC1

HCID22665795

N-[1-(4-Amino-thieno[3,2-c]pyridin-2-ylmethyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-4-(tetrahydropyran-4-yloxy)-benzenesulfonamide

C27H34N4O5S2

PRODUCTS

生成物

结构：COc1ccc2c(c1)CN(S(=O)(=O)NC(Cc1cc3c(N)nccc3s1)C(=O)N1CCC(C)CC1)CCO2

HCID86758422

未命名化合物

PROCEDURE

实验过程

This compound was prepared from 210 mg of 7-methoxy-2,3-dihydro-5H-benzo[f][1,4]-oxazepine-4-sulfonyl chloride and 210 mg of 30a using the procedure described for 58c. Yield: 70 mg (oil), (+)-FAB-MS: 560 (MH+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8fce8fcc6fac4ce5930e36186d8060bc
来源数据集: uspto-grants-2004_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06797710B2
来源说明: uspto-grants-2004_09

反应 SMILES

[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[O:12][CH2:11][CH2:10][N:9]([S:13](Cl)(=[O:15])=[O:14])[CH2:8][C:7]=2[CH:17]=1.[NH2:18][C:19]1[C:24]2[CH:25]=[C:26]([CH2:28][CH:29]([NH:39]S(C3C=CC(OC4CCOCC4)=CC=3)(=O)=O)[C:30]([N:32]3[CH2:37][CH2:36][CH:35]([CH3:38])[CH2:34][CH2:33]3)=[O:31])[S:27][C:23]=2[CH:22]=[CH:21][N:20]=1>>[NH2:18][C:19]1[C:24]2[CH:25]=[C:26]([CH2:28][CH:29]([NH:39][S:13]([N:9]3[CH2:8][C:7]4[CH:17]=[C:3]([O:2][CH3:1])[CH:4]=[CH:5][C:6]=4[O:12][CH2:11][CH2:10]3)(=[O:15])=[O:14])[C:30]([N:32]3[CH2:33][CH2:34][CH:35]([CH3:38])[CH2:36][CH2:37]3)=[O:31])[S:27][C:23]=2[CH:22]=[CH:21][N:20]=1