1,2,3,6-Tetrahydropyridine → 1-(4-(2-Pentynyloxy)pyrimidin-6-yl)pyridine

Participants

Reaction Steps

0.3 g of 4-chloro-6-(2-pentenyloxy)pyrimidine and 0.25 g of 1,2,3,6-tetrahydropyridine were mixed and left for 3 hours at room temperature. The reaction mixture was subjected to silica gel column chromatography to obtain 0.23 g of 1-(4-(2-pentynyloxy)pyrimidin-6-yl)pyridine (hereinafter, referred to as Compound (55)).

Provenance & Evidence