HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → propan-2-yl (2S)-2-amino-3-phenylpropanoate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | L-Tyrosine | HCID 6057 | — |
| Reactant | L-Phenylalanine | HCID 6140 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | propan-2-yl (2S)-2-amino-3-phenylpropanoate hydrochloride | HCID 15599949 | — |
| Product | propan-2-yl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride | HCID 67262861 | — |
Reaction Steps
Excess HCl gas was added with stirring to a suspension of L-phenylalanine or L-tyrosine in excess isopropanol. The mixture was heated to reflux for 16 h, and then the volatiles were evaporated under vacuum to give L-phenylalanine isopropyl ester hydrochloride or L-tyrosine isopropyl ester hydrochloride of sufficient purity for immediate use.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07973044B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-27542d66dd644001b946998e05c85c10 |
| Source note | uspto-grants-2011_07 |