反应详情

Pentafluoropropanal methyl hemiacetal (14.9 g, 82.8 mmol) and L-leucinol (9.7 g, 82.8 mmol) were dissolved in 100 mL of benzene and heated to reflux overnight in a flask equipped with a Dean-Stark tube. The resulting solution was cooled and concentrated to provide the title compound as an oil which was used directly in the following step.

1. temperatureheated
2. temperatureto reflux overnight in a flask
3. customequipped with a Dean-Stark tube
4. temperatureThe resulting solution was cooled
5. concentrationconcentrated