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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1009403Generated: November 2, 2026

tert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate → 5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochloride

https://huagongshe.com/reaction/1009403

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylateHCID 67067169—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
Product5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochlorideHCID 67067176216.8%

Reaction Steps

tert-Butyl N′-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate (90 mg) was dissolved in a solution of 4 N hydrogen chloride in dioxane (1 mL), and the reaction solution was stirred at room temperature for 70 minutes. The reaction solution was concentrated under reduced pressure to obtain 81 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07973033B2
Source datasetuspto-grants-2011_07
ORD IDord-fb4e17320a744b7b89fb8f96ebd2b131
Source noteuspto-grants-2011_07