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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1009690Generated: October 31, 2026

Potassium Carbonate → HCID 11740008, compound

https://huagongshe.com/reaction/1009690

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-Chloro-4-(trifluoromethyl)pyrimidineHCID 2773912—
ReactantHCID 178418879HCID 178418879—
SolventDimethylformamideHCID 6228—
ProductHCID 11740008HCID 11740008—

Reaction Conditions

Temperature80 °C

Reaction Steps

2-Chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine is dissolved in dimethyl formamide. Potassium carbonate and 2-chloro-4-trifluoromethyl-pyrimidine are added and the reaction mixture is stirred at about 80° C. overnight. It is obtained 2-[4-(2-chloro-pyridin-4-ylethynyl)-2-methyl-imidazol-1-yl]-4-trifluoromethyl-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07973165B2
Source datasetuspto-grants-2011_07
ORD IDord-4c39d5daab5c479999de6be21be88b45
Source noteuspto-grants-2011_07