(3,5-Difluorophenyl)boronic acid → HCID 11472961, compound

HRID 1009713Notes

Reaction equation

HRID 1009713 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[F:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[C:21]([F:23])[CH:22]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:19]3[CH:18]=[C:17]([F:16])[CH:22]=[C:21]([F:23])[CH:20]=3)[CH:14]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 2734338(3,5-Difluorophenyl)boronic acidHCID 178418879HCID 178418879, compound

Product 1

HCID 11472961HCID 11472961, compound

Procedure

The title compound, MS: m/e=330.3 (M+H+), was prepared in accordance with the general method of example 7 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 3,5-difluorobenzene boronic acid.

Sources & evidence

ORD record
ord-f78bdaebd35c43e79815547f7745c826
Source dataset
uspto-grants-2011_07
Patent number
US07973165B2

Reaction notes

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