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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1009714Generated: October 31, 2026

3-Fluoro-4-methylbenzeneboronic acid → 2-Chloro-4-[1-(3-fluoro-4-methyl-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

https://huagongshe.com/reaction/1009714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-methylbenzeneboronic acidHCID 2782674—
ReactantHCID 178418879HCID 178418879—
Product2-Chloro-4-[1-(3-fluoro-4-methyl-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridineHCID 86595315—

Reaction Steps

The title compound, MS: m/e=326.4 (M+H+), was prepared in accordance with the general method of example 7 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 3-fluoro-4-methyl-benzene boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07973165B2
Source datasetuspto-grants-2011_07
ORD IDord-855a2ce329294fbda2dd62ffefadc962
Source noteuspto-grants-2011_07