2-Chloropyrimidine → HCID 24963371, compound

HRID 1009721Notes

Reaction equation

HRID 1009721 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.Cl[C:17]1[N:22]=[CH:21][CH:20]=[CH:19][N:18]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:17]3[N:22]=[CH:21][CH:20]=[CH:19][N:18]=3)[CH:14]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 744042-ChloropyrimidineHCID 178418879HCID 178418879, compound

Product 1

HCID 24963371HCID 24963371, compound

Procedure

The title compound, MS: m/e=296.5 (M+H+), was prepared in accordance with the general method of example 3 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2-chloro-pyrimidine.

Sources & evidence

ORD record
ord-53475a45507c487fbd82b11e99e2639f
Source dataset
uspto-grants-2011_07
Patent number
US07973165B2

Reaction notes

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