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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1009728Generated: October 27, 2026

2-Chloropyridine-5-boronic acid → 4-[1-(6-Chloro-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine-2-carbonitrile

https://huagongshe.com/reaction/1009728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloropyridine-5-boronic acidHCID 3845034—
ReactantHCID 178432714HCID 178432714—
Product4-[1-(6-Chloro-pyridin-3-yl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine-2-carbonitrileHCID 24963718—

Reaction Steps

The title compound, MS: m/e=320.0, 322.1 (M+H+), was prepared in accordance with the general method of example 7 from 4-(2-Methyl-1H-imidazol-4-ylethynyl)-pyridine-2-carbonitrile and 6-chloro-3-pyridinyl-boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07973165B2
Source datasetuspto-grants-2011_07
ORD IDord-830c6006ce4445878318d4373eb31174
Source noteuspto-grants-2011_07