Lithium Hydroxide → HCID 86628830, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 8, N-(4-methylthiazol-2-yl)-2-[4-(7-methoxy-6-methoxycarbonylquinolin-4-yloxy)phenyl]acetamide was reacted with lithium hydroxide to give the title compound in 97% yield; 1H NMR: (DMSOd6) 2.26 (d, 3H), 3.83 (s, 2H), 4.01 (s, 3H), 6.63 (d, 1H), 6.76 (s, 1H), 7.34 (d, 2H), 7.51 (d, 2H), 7.57 (s, 1H), 8.62 (s, 1H), 8.78 (d, 1H); Mass Spectrum: M+H+ 450.

Provenance & Evidence