Acetyl chloride → HCID 57659376, compound

Participants

Reaction Steps

The product of Step 2 (52 mg) was dissolved in dichloromethane (10 ml), treated with triethylamine (0.07 ml) and acetyl chloride (0.014 ml) for 1 h. The reaction mixture was diluted with dichloromethane, washed with water. The organic phase was concentrated to give (3aR,9bS)-tert-butyl 1-acetyl-1,2,3,3a,4,9b-hexahydrospiro[benzo[g]indole-5,4′-piperidine]-1′-carboxylate 14 (47 mg). LC-MS: m/e=329.6 (M+-tBu, 100%). Rt=3.21 min.

Provenance & Evidence