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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1009897Generated: October 30, 2026

HCID 86635042, compound → HCID 57847114, compound

https://huagongshe.com/reaction/1009897

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86635042HCID 86635042—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 57847114HCID 57847114105.2%

Reaction Steps

A mixture of benzyl(3aR*,4R*,9bR*)-4-(4-fluorophenyl)-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-c]quinoline-1-carboxylate (500 mg, 1.24 mmol) and 10% palladium on carbon (50% aqueous, 0.3 g) in ethanol (20 ml) was stirred at room temperature under hydrogen atmosphere for 2 hrs. The catalyst was filtered off, and the mixture was washed with ethanol. The solvent was evaporated under reduced pressure to give the title compound (350 mg, ca. 100%) as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07973163B2
Source datasetuspto-grants-2011_07
ORD IDord-c7d1236e17bf40428e89559234516e0b
Source noteuspto-grants-2011_07