HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86635042, compound → HCID 57847114, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86635042 | HCID 86635042 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57847114 | HCID 57847114 | 105.2% |
Reaction Steps
A mixture of benzyl(3aR*,4R*,9bR*)-4-(4-fluorophenyl)-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-c]quinoline-1-carboxylate (500 mg, 1.24 mmol) and 10% palladium on carbon (50% aqueous, 0.3 g) in ethanol (20 ml) was stirred at room temperature under hydrogen atmosphere for 2 hrs. The catalyst was filtered off, and the mixture was washed with ethanol. The solvent was evaporated under reduced pressure to give the title compound (350 mg, ca. 100%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07973163B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-c7d1236e17bf40428e89559234516e0b |
| Source note | uspto-grants-2011_07 |