HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethyl-1,3-dioxane-4,6-dione → HCID 67202400, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Methyl 5-aminofuran-2-carboxylate | HCID 5072225 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 67202400 | HCID 67202400 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
Methyl 5-amino-2-furoate (4 g) by Lancaster was added to a mixed solution of triethyl orthoformate (20 ml) and isopropyl alcohol (20 ml), and then Meldrum acid (4.5 g) was added and the mixture was heated and stirred at 100° C. for 1 hour. After cooling, the precipitated crystals were filtered out and washed with isopropyl alcohol to obtain the title compound (7.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07973160B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-6a9db0bd6a554b85b513a33d0a9fed00 |
| Source note | uspto-grants-2011_07 |