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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1010358Generated: October 31, 2026

Toluene → HCID 58931434, compound

https://huagongshe.com/reaction/1010358

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
Reactant4-Fluorophenyl isocyanateHCID 70955—
ReactantHCID 58931477HCID 58931477—
SolventAcetonitrileHCID 6342—
ProductHCID 58931434HCID 58931434—

Reaction Steps

After adding toluene (1 ml), acetonitrile (0.5 ml) and 4-fluorophenyl isocyanate (0.03 ml) to 4-(6-phenyl-furo[2.3-d]pyrimidin-4-yloxy)phenylamine (40 mg), the mixture was heated to reflux for 30 minutes. After cooling, the precipitated crystals were filtered out and washed with toluene to obtain the title compound (42 mg) as light yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07973160B2
Source datasetuspto-grants-2011_07
ORD IDord-ff8cf1a65e6d4262abf0c760f33c34be
Source noteuspto-grants-2011_07