m-Chloroperbenzoic acid → HCID 59707964, compound

Participants

Reaction Steps

28.1 g (0.1 mole) of tris(2-(methoxymethoxy)ethyl)-amine was dissolved in 85 g of dichloromethane, which was ice cooled. To the solution, 26.5 g (0.1 mole) of 65% pure m-chloroperbenzoic acid in 250 g of dichloromethane was added dropwise at such a rate that the mixture might not exceed 5° C. The mixture was allowed to mature for one hour at room temperature. The reaction solution was concentrated below 30° C. and the residue was purified by column chromatography (basic alumina, elute; dichloromethane/methanol). The eluate was concentrated whereupon the desired compound solidified. The amount was 27.3 g and the yield was 92*.

Provenance & Evidence