3-(Phenylsulfonyl)-8-quinolinamine → 8-Amino-6-methyl-3-phenylsulfonylquinoline

HRID 1010590Notes

Reaction equation

HRID 1010590 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([N+:12]([O-])=O)[CH:11]=1)[N:8]=[CH:7][C:6]([S:15]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)(=[O:17])=[O:16])=[CH:5]2.NC1C=CC=C2C=1N=CC(S(C1C=CC=CC=1)(=O)=O)=C2>>[NH2:12][C:10]1[CH:11]=[C:2]([CH3:1])[CH:3]=[C:4]2[C:9]=1[N:8]=[CH:7][C:6]([S:15]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)(=[O:17])=[O:16])=[CH:5]2

Participants

3

Reactant 2

HCID 534255023-(Phenylsulfonyl)-8-quinolinamineHCID 673138706-Methyl-8-nitro-3-phenylsulfonylquinoline

Product 1

HCID 673138648-Amino-6-methyl-3-phenylsulfonylquinoline

Procedure

Prepared from 6-methyl-8-nitro-3-phenylsulfonylquinoline (D24) in an analogous process to that described in Description 5 (D5);

Sources & evidence

ORD record
ord-8dd1356cb1974568a8ed6335bdeec8ba
Source dataset
uspto-grants-2011_07
Patent number
US07977337B2

Reaction notes

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