Ethyl orthoformate → HCID 67021375, compound

Participants

Reaction Steps

A mixture of 0.356 g of [4-(3-amino-pyridin-4-ylamino)-phenyl]-acetic acid methyl ester and 9.2 ml of triethyl orthoformate is stirred and refluxed for 2 hours. The mixture obtained is allowed to cool to rt and is concentrated in vacuo. (4-Imidazo[4,5-c]pyridin-1-yl-phenyl)-acetic acid methyl ester is obtained in the form of a solid: ES-MS: 268.1 [M+H]+; single peak at tR=2.03 min (System 1).

Provenance & Evidence