HCID 4885471, compound → HCID 22724463, compound

Participants

Reaction Steps

2 g of a suspension of [4-(3-nitro-pyridin-2-ylamino)-phenyl]-acetic acid methyl ester and 0.600 g of Raney Ni in 40 ml of MeOH (40 mL) is stirred for 4 hours at rt under a hydrogen atmosphere. The mixture obtained is filtered through a pad of Celite and concentrated. [4-(3-Amino-pyridin-2-ylamino)-phenyl]-acetic acid methyl ester is obtained in the form of a solid: ES-MS: 258.0 [M+H]+; tR=2.30 min (System 1); Rf=0.15 (Hexane/EtOAc, 1:1).

Provenance & Evidence