AP-24592 → HCID 11993679, compound

Participants

Reaction Steps

is obtained analogously to the method as described in Example 1 but using (4-benzoimidazol-1-yl-phenyl)-acetic acid instead of (4-imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid and 4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenylamine instead of 3′-bromo-2-trifluoromethyl-biphen-4-ylamine as a starting material (see WO 03/099771). ES-MS: 508.0 [M+H]+; single peak at tR=2.84 min (System 1); Rf=0.10 (CH2Cl2/MeOH+1% NH3aq, 9:1). Starting material is prepared as follows: Step 2.1: (4-Benzoimidazol-1-yl-phenyl)-acetic acid

Provenance & Evidence