HCID 131729014, compound → HCID 131729013, compound

Participants

Reaction Steps

227 mg of the compound [86-3] was dissolved in 7 mL of methanol, and 114 mg of a 20% palladium/carbon catalyst was added thereto. The mixture was stirred at room temperature for 1 hour under hydrogen atmosphere. The catalyst was filtered through Celite, and the filtrate was concentrated under reduced pressure to obtain 188 mg of tert-butyl((1S)-1-{4-[1-hydroxy-2-methyl-2-(methylamino)propyl]phenyl}ethyl)carbamate [86-4] (hereinafter, referred to as the compound [86-4]).

Provenance & Evidence