HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-tert-Butylanilino)-3-methoxy-2-methylpyridine → 4-(4-tert-Butylcyclohexylamino)-3-methoxy-2-methylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-tert-Butylanilino)-3-methoxy-2-methylpyridine | HCID 19693953 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(4-tert-Butylcyclohexylamino)-3-methoxy-2-methylpyridine | HCID 54451262 | — |
Reaction Steps
1 g of 4-(4-tert-butylanilino)-3-methoxy-2-methylpyridine in 20 ml of methanol, 3.7 ml of 2N HCl and 1.3 ml of water are hydrogenated at room temperature and normal pressure until absorption of hydrogen has ended using 1 g of rhodium on alumina (5% strength). After filtering and concentrating 1 g of syrup remains=100% isomer mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05723450 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-61a0177588e440db829d21a8578b91c1 |
| Source note | uspto-grants-1998_03 |