Phthalic Anhydride → 2-{[(Tetrahydro-3-furanylmethyl)oxy]carbonyl}benzoic acid

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of phthalic anhydride (7.41 gm) and tetrahydro-3-furanmethanol were heated with stirring at 130° C. under nitrogen. After 1.5 h, the clear liquid was allowed to cool, treated with water and extracted with EtOAc (×3). The combined organics were dried by passing through a hydrophobic frit and evaporated to a clear oil which crystallised on trituration with light petrol. The solid was filtered, washed and dried, yield 11.93 gm.

Herkunft & Nachweise