HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon tetrabromide → 3-(2-Bromoethyl)tetrahydro-2H-pyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon tetrabromide | HCID 11205 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Tetrahydro-2H-pyran-3-ethanol | HCID 55264768 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(2-Bromoethyl)tetrahydro-2H-pyran | HCID 54494306 | — |
Reaction Steps
A solution of triphenylphosphine (725 mg, 2.77 mmol) in DCM (4 ml) was added dropwise with water-bath cooling to a solution of 2-(tetrahydro-2H-pyran-3-yl)ethanol (300 mg, 2.304 mmol) and carbon tetrabromide (917 mg, 2.77 mmol) in DCM (6 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07977344B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-4102282daa87473183cb6f5910ef7ecf |
| Source note | uspto-grants-2011_07 |