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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011076Generated: November 1, 2026

2-(3-Bromopropyl)oxolane → N2-Butyl-8-(methyloxy)-9-[3-(tetrahydro-2-furanyl)propyl]-9H-purine-2,6-diamine

https://huagongshe.com/reaction/1011076

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Bromopropyl)oxolaneHCID 15783712—
ReactantHCID 178448877HCID 178448877—
ProductN2-Butyl-8-(methyloxy)-9-[3-(tetrahydro-2-furanyl)propyl]-9H-purine-2,6-diamineHCID 57699716—

Reaction Steps

Prepared similarly to Intermediate 216 from N2-butyl-8-(methyloxy)-3H-purine-2,6-diamine trifluoroacetate and 2-(3-bromopropyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-d7a03069f8944141ab01ed7bd9c193da
Source noteuspto-grants-2011_07