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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011081Generated: November 1, 2026

3-(4-Bromobutyl)oxolane → N2-Butyl-8-(methyloxy)-9-[4-(tetrahydro-3-furanyl)butyl]-9H-purine-2,6-diamine

https://huagongshe.com/reaction/1011081

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Bromobutyl)oxolaneHCID 57699612—
ReactantHCID 178448877HCID 178448877—
ProductN2-Butyl-8-(methyloxy)-9-[4-(tetrahydro-3-furanyl)butyl]-9H-purine-2,6-diamineHCID 57699689—

Reaction Steps

Prepared similarly to Intermediate 216 from N2-butyl-8-(methyloxy)-3H-purine-2,6-diamine trifluoroacetate and 3-(4-bromobutyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-2b2dd2b53988466daf59ac1563ae7750
Source noteuspto-grants-2011_07