HCID 11790746, compound → HCID 57699636, compound

HRID 1011083Notes

Reaction equation

HRID 1011083 reaction equation
FC(F)(F)C(O)=O.[CH2:8]([NH:12][C:13]1[NH:21][C:20]2[C:16]([N:17]=[C:18]([O:22][CH3:23])[N:19]=2)=[C:15]([NH2:24])[N:14]=1)[CH2:9][CH2:10][CH3:11].Br[CH2:26][CH2:27][CH2:28][CH2:29][CH:30]1[CH2:35][CH2:34][CH2:33][CH2:32][O:31]1>>[CH2:8]([NH:12][C:13]1[N:21]=[C:20]2[C:16]([N:17]=[C:18]([O:22][CH3:23])[N:19]2[CH2:26][CH2:27][CH2:28][CH2:29][CH:30]2[CH2:35][CH2:34][CH2:33][CH2:32][O:31]2)=[C:15]([NH2:24])[N:14]=1)[CH2:9][CH2:10][CH3:11]

Participants

3

Reactant 2

HCID 11790746HCID 11790746, compoundHCID 178448877HCID 178448877, compound

Product 1

HCID 57699636HCID 57699636, compound

Procedure

Prepared similarly to Intermediate 220 from N2-butyl-8-(methyloxy)-3H-purine-2,6-diamine trifluoroacetate and 2-(4-bromobutyl)tetrahydro-2H-pyran.

Sources & evidence

ORD record
ord-abc127bbe18d4a6383029baa0f5e8ba6
Source dataset
uspto-grants-2011_07
Patent number
US07977344B2

Reaction notes

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