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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011092Generated: November 1, 2026

(3S)-3-(2-bromoethyl)oxolane → 2-(Butyloxy)-8-(methyloxy)-9-[2-[(3R)-tetrahydro-3-furanyl]ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011092

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-3-(2-bromoethyl)oxolaneHCID 52324314—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-[2-[(3R)-tetrahydro-3-furanyl]ethyl]-9H-purin-6-amineHCID 57699766—

Reaction Steps

Prepared similarly to Intermediate 215 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and (3S)-3-(2-bromoethyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-8748cb30ba6c4266881a90267b044d2f
Source noteuspto-grants-2011_07