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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011094Generated: November 1, 2026

3-(4-Bromobutyl)oxolane → 2-(Butyloxy)-8-(methyloxy)-9-[4-(tetrahydro-3-furanyl)butyl]-9H-Purin-6-amine

https://huagongshe.com/reaction/1011094

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Bromobutyl)oxolaneHCID 57699612—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-[4-(tetrahydro-3-furanyl)butyl]-9H-Purin-6-amineHCID 57699592—

Reaction Steps

Prepared similarly to Intermediate 216 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 3-(4-bromobutyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-dcfb20b0eaf0492ca42732f1c7b0cd09
Source noteuspto-grants-2011_07