HCID 57699648, compound → HCID 57699769, compound

HRID 1011102Notes

Reaction equation

HRID 1011102 reaction equation
FC(F)(F)C(O)=O.[CH2:8]([O:12][C:13]1[NH:14][C:15]([NH2:24])=[C:16]2[C:20]([N:21]=1)=[N:19][C:18]([O:22][CH3:23])=[N:17]2)[CH2:9][CH2:10][CH3:11].Br[CH2:26][CH2:27][CH2:28][CH:29]1[CH2:34][CH2:33][O:32][C:31]([CH3:36])([CH3:35])[CH2:30]1>>[CH2:8]([O:12][C:13]1[N:21]=[C:20]2[C:16]([N:17]=[C:18]([O:22][CH3:23])[N:19]2[CH2:26][CH2:27][CH2:28][CH:29]2[CH2:34][CH2:33][O:32][C:31]([CH3:35])([CH3:36])[CH2:30]2)=[C:15]([NH2:24])[N:14]=1)[CH2:9][CH2:10][CH3:11]

Participants

3

Reactant 2

HCID 57699648HCID 57699648, compoundHCID 178450357HCID 178450357, compound

Product 1

HCID 57699769HCID 57699769, compound

Procedure

Prepared similarly to Intermediate 224 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 4-(3-bromopropyl)-2,2-dimethyltetrahydro-2H-pyran.

Sources & evidence

ORD record
ord-8197a0dee3a24e11b8db39590613729b
Source dataset
uspto-grants-2011_07
Patent number
US07977344B2

Reaction notes

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