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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011104Generated: October 26, 2026

2-(2-Bromoethyl)oxolane → 2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[2-(tetrahydro-2-furanyl)ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011104

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Bromoethyl)oxolaneHCID 53691871—
ReactantHCID 178494009HCID 178494009—
Product2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[2-(tetrahydro-2-furanyl)ethyl]-9H-purin-6-amineHCID 57699779—

Reaction Steps

Prepared similarly to Intermediate 213 from 2-[(2-cyclopropylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 2-(2-bromoethyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-9a325734f18b4e9aad97c8827cc30883
Source noteuspto-grants-2011_07