3-(3,4,5-Trimethoxyphenyl)benzyl chloride → 1-(tert-butoxycarbonyl)-4-[N-(4-fluorophenyl)-N-[3-(3,4,5-trimethoxyphenyl)benzyl]amino]piperidine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:22][O:23][c:24]1[cH:25][c:26](-[c:34]2[cH:35][c:36]([CH2:37][Cl:38])[cH:39][cH:40][cH:41]2)[cH:27][c:28]([O:32][CH3:33])[c:29]1[O:30][CH3:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([c:15]2[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]2)[CH2:37][c:36]2[cH:35][c:34](-[c:26]3[cH:25][c:24]([O:23][CH3:22])[c:29]([O:30][CH3:31])[c:28]([O:32][CH3:33])[cH:27]3)[cH:41][cH:40][cH:39]2)[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-819d2ba9d0844803b2557222c8f25856
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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