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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1011110Generated: November 2, 2026

3-(3-Bromopropyl)oxolane → 2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[3-(tetrahydro-3-furanyl)propyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1011110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Bromopropyl)oxolaneHCID 57699778—
ReactantHCID 178494009HCID 178494009—
Product2-[(2-Cyclopropylethyl)oxy]-8-(methyloxy)-9-[3-(tetrahydro-3-furanyl)propyl]-9H-purin-6-amineHCID 57699810—

Reaction Steps

Prepared similarly to Intermediate 216 from 2-[(2-cyclopropylethyl)oxy]-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 3-(3-bromopropyl)tetrahydrofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07977344B2
Source datasetuspto-grants-2011_07
ORD IDord-5dca88e0ac6345f9aa540a987c3537be
Source noteuspto-grants-2011_07